On behalf of myself and the MigreLief Team at Akeso Health Sciences, I would like to thank you for supporting Akeso’s goal of improving the quality of life for migraine sufferers worldwide. In part, because of your support we are reaching more men, women, and children whose lives are disrupted by this debilitating disorder.
As a way of saying thank you, I would like to share, what I believe to be extremely valuable science that you and your loved ones can begin implementing today to significantly reduce your risk of developing chronic degenerative diseases and increase the likelihood of living to a ripe old age while remaining vibrant, strong, energetic, and young-looking.
Chronic degenerative diseases, to name a few, include:
- Heart disease
- Cancer
- Arthritis
- Diabetes
- Asthma
- Alzheimer’s disease
Though seemingly distinct and different diseases, all have remarkable similarities when we measure certain biomarkers in the blood and spinal fluid that are acknowledged indicators or precursors of disease progression.
Staying healthy is an important commitment to make to yourself. As the saying goes, “An ounce of prevention is worth a pound of cure.” Believe it or not, a lack of illness isn’t necessarily an indicator of good health. You’ve heard stories of people who seem to be in good health, then suddenly experience a serious health crisis. Taking a proactive approach to health will reduce your chances of being caught off guard and increase your chances of living a long, happy, and healthy life.
Three of the most important destructive aging and disease-causing phenomenon that occur and can be measured in the body are:
- Oxidative Stress
- Systemic Inflammation
- Excessive Glycation – (the damage that sugar does to tissue and cellular proteins).
Oxidative Stress – Many of you have probably heard about the damage that “free radicals” can do to our bodies. Free radicals are atoms or molecules that are missing an electron and steal electrons from healthy cells and damage them or cause them to die or mutate (cancer). Removal of the electron from the healthy cell by the free radical is called oxidation and thus the term “oxidative stress”. Free radicals can cause harm if their levels become too high in your body. They’re linked to multiple illnesses, including diabetes, heart disease, and cancer.
Your body has its own antioxidant defenses to keep free radicals in check. However, antioxidants are also found in food, especially in fruits, vegetables, and other plant-based, whole foods. Several vitamins, such as vitamins E and C, are effective antioxidants.
To reduce the risk of developing chronic degenerative diseases and prevent accelerated aging, we need to control oxidative stress!
Systemic Inflammation – Inflammation, when under control is actually a signal used by the body to call white blood cells to an injured/damaged area within our bodies to start healing. For example, if a cut becomes infected it becomes inflamed. The inflammation is actually a signal for certain types of white blood cells to come to the injured area to “clean” up the infection. Once the wound has healed the inflammation goes away and we return to normal. But excessive oxidative stress caused by high sugar diets lacking antioxidant-rich foods (fruits and vegetables) promotes a consistent “low grade” level of circulating inflammatory compounds. Over time and if not checked, this low-grade inflammation erodes our bodies, brains, and other organs and accelerates oxidative stress and the on-going damage that occurs over time.
To reduce the risk of developing chronic degenerative diseases and prevent accelerated aging, we need to control systemic inflammation!
Excessive Glycation – The chemical process by which part of a sugar molecule attaches to and changes/destroys a protein molecule is referred to as glycation.
Many of you have probably heard how Type II diabetes has become rampant in our American population. Due to poor diets, many of us stop responding efficiently to the insulin produced by the pancreas. Insulin’s role is to make sure the sugar in our blood is transferred to the cells where it can be used for energy and carrying out cellular functions.
When we become less sensitive to insulin, more sugar “hangs around” in the blood and as the blood circulates the sugar in it does damage to organs like our hearts, kidneys, lungs, brains, and eyes. This is why heart disease is associated with diabetes.
To reduce the risk of developing chronic degenerative diseases and prevent accelerated aging, we need to control “excessive glycation.”
IF WE WANT TO LEAD LONG, PRODUCTIVE, AND HEALTHY LIVES WELL INTO OUR 80’S, 90’S AND BEYOND, WE NEED TO CONTROL – “OXIDATIVE “STRESS,” “SYSTEMIC INFLAMMATION,” AND “EXCESSIVE GLYCATION!”
Here’s how to do it… Consume the following vitamins and herbs:
1- The Indian spice TUMERIC and its active ingredient CURCUMIN – Tumeric is the yellow spice that is used in Indian cooking. Extracts of turmeric that contain 95% curcumin are among the most medicinally researched herbal compounds in the world. From cancer to heart disease, to Alzheimer’s and arthritis, there are numerous human studies showing the incredible protective and healing powers of curcumin. Its benefits extend to Crohn’s disease, ulcerative colitis, irritable bowel disease, tropical pancreatitis, peptic ulcer, gastric ulcer, idiopathic orbital inflammatory pseudotumor, gastric inflammation, psoriasis, acute coronary syndrome, atherosclerosis, diabetes, diabetic nephropathy, lupus nephritis, renal conditions, acquired immunodeficiency syndrome, and more.
turmeric
Curcumin is at the same time a powerful antioxidant, powerful anti-inflammatory, and also demonstrates some ability to slow down glycation. So there is no wonder why it is at the top of my list of natural supplements to take if you want to live to 100 years or more and maintain exceptional health, and resist disease and aging.
DOSE: 1000-1500 mg a day of the turmeric extract. Make sure it states it is 95% curcumin on its label.
2- GREEN TEA EXTRACT – Many of you have heard about the multiple health benefits of drinking green tea. I suggest in addition to drinking it, that you take green tea extract as well because you can never be sure the specific green tea you are drinking has any or enough of the specific phyto-compounds in it that make it so healthy and protective. Several studies that have been published indicate that combining green tea with curcumin is synergistic and enhances the protective and health-promoting benefits of each.
DOSE: 800-1000 mg a day of a green tea extract in capsule or tablet form that contains 50% EGCG (the most important active compound found in green tea).
3– R-ALPHA-LIPOIC ACID – This dietary supplement helps to prevent the advanced glycation end products caused by sugar that do harm to our cells and tissues. It also helps us to maintain our ability to remain sensitive to insulin and reduces the risk of developing Type II diabetes.
In addition, lipoic acid protects the energy-producing organelles in our cells called mitochondria. As we age the effects of oxidative stress, inflammation and toxins damage the energy-producing ability of our mitochondria and thus we experience the lack of energy often associated with advancing age. Lipoic acid helps to reduce this mitochondrial damage from occurring.
DOSE: 400-600 mg a day of R-alpha-lipoic acid. (Be sure that the supplement you get says “R” lipoic acid as it is believed to be the active isomer of this compound.)
TAKE A MULTIPLE VITAMIN – To the above recommendations, I strongly suggest that you take a daily comprehensive multiple vitamin/mineral product (that contains at least 25 mg each of Vitamin B-1, 2, 3, 5 and 400-800 mcg of folic acid and 100 mcg of vitamin B-12).
Furthermore, make sure that you add at least 30 grams of soluble and insoluble fiber into your diet daily. Hi-fiber cereals that contain 8+ grams per serving are good places to start. Then you can sprinkle either psyllium or ground FLAX SEED on top of the cereals or into yogurt or salads to further increase your fiber intake. You may also add to blended smoothies.
Healthy Items Checklist:
Tumeric (95% Curcumin): 1000-1500 mg/day
Green Tea Extract (50% EGCG): 800-1000 mg/day
R-Alpha-Lipoic Acid – 400-800 mcg/day
plus
Multiple Vitamin – containing at least; 25mg of Vit B-1, B-2, B-3 B-5, 100 mcg of B-12 and 400-800 folic acid
Ground Flaxseed or Psyllium -30 grams (sprinkled on food or mixed into smoothies etc.)
Finally and MOST IMPORTANTLY, reestablishing healthy sleep patterns is the most powerful tool you can rely on to maintain good health and extend your life. Sleep affects all aspects of our lives. Deep restorative sleep is where the body and internal systems regenerate themselves. Sleep improves immune function, protects against cellular damage, supports proper brain function, and improves focus, memory, concentration, learning, and productivity. Healthy sleep also lowers the risk of heart disease, diabetes, stroke dementia, and obesity while sleep loss activates undesirable markers of inflammation and cell damage.
If falling asleep, staying asleep, or reaching deep, restorative sleep is difficult for you, consider adding a quality natural sleep supplement to your nightly routine.
I sincerely hope that you take this advice to heart and follow it daily. It will make a profound difference in how you age and how young and healthy you stay throughout the upcoming years.
To the Best of Health,
Curt Hendrix, M.S. C.N.N. C.N.S.
Chief Scientific Officer, Akeso Health Sciences
Migraine Supplement Pioneer
